The former Cardiff City man, Collins has a calf injury that saw miss the Welsh national side’s trip to Cyrpus last week.
Nigel’s injury could see him miss up to six weeks of action after sustaining a small crack in the ankle bone under a heavy challenge during the West Brom game.
On a positive note though, first-choice goalkeeper Roy Carroll looks set to return between the sticks for the local derby against Tottenham on Sunday after recovering from his freak knee injury.